The opening scene introduces 11-year-old Eli Miller playing outside under the warm sun when he suddenly experiences severe coughing, collapses, and struggles to breathe. His skin reddens, and he cries for help. Eli then wakes up inside a sterile bubble, revealing it was just a dream. He suffers from a rare disease that triggers severe allergic reactions to the outdoors, forcing him to live in protective gear. Despite these challenges, Eli's mother shows unwavering love, expressing affection through the plastic bubble to ensure he doesn't feel lonely.