In the 22nd century, the medical rescue ship Nightingale is on patrol when its AI, Sweetie, interrupts Benjamin’s nap to play chess. Meanwhile, crew members Yerzy and Danika are involved in a romantic encounter, while Captain Marley analyzes Tom and Jerry. Evers conducts a checkup on Nick, a recovering addict, and encourages him to socialize. After playing card games with Benjamin, Nick questions Evers' disdain for him, leading to a conversation about her negative views on addiction. Suddenly, Sweetie alerts them to a distress signal from Titan 37, an ice mining operation, which has taken five days to reach them and is unusually direct. The crew rushes to investigate.