In Raccoon City, Dr. Marcus of Umbrella Corporation discovers the T-virus, curing his daughter's aging disease. The virus becomes a marketed medicine. Later in South Africa, a child turns undead after taking the medicine. Marcus and Issacs clash over the T-virus's fate, leading to Marcus's death. Issacs becomes the company's leader. Red Queen AI, resembling Marcus's daughter, is created. A virus outbreak devastates Raccoon City despite government bombing. The T-virus threat persists.