In the Raffy Tulfo episode titled "Mister, Nag-Vlog sa Isang Sikat na Hotel," the narrative likely focuses on a man who vlogs during his stay at a popular hotel, potentially capturing moments that lead to unexpected or controversial situations. This could involve interactions with staff, other guests, or issues related to the hotel's service.

Raffy Tulfo’s involvement would address any problems that arise from the vlogging, such as complaints from hotel management or misunderstandings with other guests. Themes of privacy, customer experience, and the impact of social media on businesses are highlighted as the story unfolds. The episode may explore the balance between sharing experiences online and respecting the environment one is in, all while providing entertainment and insights into the world of hospitality.