The show starts in Berlin, Germany, where John Fontanelli, a bike messenger, receives an order to deliver a package to an unknown location. He is approached by an old man claiming he might be the potential heir to a large estate. The old man gives him €2,000 in exchange for his saliva for a DNA check. Initially skeptical, John decides to play along as the old man is paying him well. He is whisked away to Florence, where he learns he is a descendant of Gako Fontanelli, a powerful man who lived 500 years ago, making him the heir to the world's richest inheritance.