When all Earths of the Multiverse are under attack, a new Justice League forms with heroes from parallel universes to correct history. In Crisis on Infinite Earths, a dragon threatens Earth 38, prompting Supergirl to save the city with her powers. The looming danger of antimatter destruction alerts the heroes, including Superman and Lois on Argo City. They must send their son to safety on Earth as the crisis escalates. Meanwhile, on Earth 1, a team of superheroes gathers to stop the impending catastrophe. With the help of Quantum Towers, the heroes plan to save their world from annihilation while also rescuing Superman's son trapped in another time.